Biofabrication uses cells or biologics as basic building blocks in which biological models, systems, devices and products are manufactured. Biofabrication techniques encompass a broad range of physical, chemical, biological, and/or engineering process, with various applications in tissue science and engineering, regenerative medicine, disease pathogeneses and drug testing studies, biochips and biosensors, cell printing, patterning and assembly, and organ printing.
The Program for Biofabrication at Drexel integrates computer-aided tissue engineering, modern design and manufacturing, biomaterials and biology in modeling, design, and biofabrication of tissue scaffolds, tissue constructs, micro-organ, tissue models. The on-going research focuses on: bio-tissue modeling, bio-blueprint modeling, scaffold informatics modeling, biomimetic design of tissue scaffold, additive manufacturing of tissue scaffolds, cell printing and organ printing.
The facilities at the Biofabrication Laboratory include:
1) state-of-the-art computer-aided design/engineering/manufacturing (CAD/CAE/CAM) software, medical image processing and 3D reconstruction software, and in-house developed heterogeneous modeling and homogenization software;
2) proprietary multi-nozzle cell deposition system for direct cell writing and construction of tissue precursors and micro-organs;
3) proprietary precision extruding deposition system for fabrication of 3D biopolymer tissue scaffolds;
4) commercial available 3DP freeform fabrication system for bio-physical modeling;
5) plasma instrument for surface treatment and surface functionlization
6) MTS universal testing system
7) laboratory for cell and tissue culture study.